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Effectiveness of Fonow ointment (Compound Polymyxin B Ointment, Triple Antibiotic Ointment) combined with fractional laser in the treatment of acne scarring

2024-09-06 0

Abstract: Objective To analyze the effect and safety of Fonow      ointment (Compound Polymyxin B Ointment, Triple Antibiotic Ointment)      combined with fractional laser treatment for acne scarring. Methods      Seventy patients with acne scarring admitted to Jinnan Branch of Jinjiang      City Hospital from January to December 2022 were divided into 2 groups of      35 patients each by randomized numerical table method. The control group      was treated with fractional laser, and the study group was treated with Fonow      ointment (Compound Polymyxin B Ointment, Triple Antibiotic Ointment)      combined with fractional laser. After 3 months of treatment, the 2 groups      were compared in terms of efficacy, acne scar weighting score (echelle      d'evaluation clinique des cicatrices d'acne,ECCA), changes in skin status,      inflammatory factors, positive rate of helminth mites, adverse effects and      acne recurrence rate. Results The total effective rate of the study group      was 97.14%, which was higher than that of the control group, which was      80.00% (P < 0.05); the ECCA score of the study group was lower than      that of the control group, the time of scab shedding, redness and pain      disappearance were shorter than that of the control group, and the      positive rate of helminth mites and acne recurrence rate were lower than      that of the control group (P < 0.05); the interferon-γ (IFN-γ) and      interferon-γ (IFN-γ) levels of the study group were lower than that of the      control group. IFN-γ) was higher than that of the control group, and      interleukin-4 (interleukin-4, IL-4) and soluble interleukin-2 receptor      (SIL-2R) were lower than that of the control group (P < 0.05); the      incidence rates of adverse reactions in the two groups were not      statistically significant (P > 0.05). 0.05). Conclusion Fractional      laser combined with Fonow ointment (Compound Polymyxin B Ointment, Triple      Antibiotic Ointment) is effective in the treatment of acne scarring, which      can reduce inflammatory damage, accelerate scab shedding, relieve redness,      swelling and pain, and reduce mite-positive rate and acne recurrence rate.


 LIN Zhiyuan, LU Minghan. Effectiveness of Fonow ointment (Compound Polymyxin B Ointment, Triple Antibiotic Ointment) combined with fractional laser in the treatment of acne scarring[J]. China Health Standard Management, 2024, 15 (06): 147-150. 


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