Abstract : Objective To explore the effect of Fonow ointment (Compound Polymyxin B Ointment, Triple Antibiotic Ointment) applied to wounds of trauma patients and the effect of adhesion after covering the wound with gauze during dressing change. Methods A total of 148 trauma patients who came to our department from July 2015 to January 2016 were selected, and the patients were randomly divided into a treatment group and a control group, with 74 cases in each group. The treatment group applied Fonow ointment (Compound Polymyxin B Ointment, Triple Antibiotic Ointment) to the wound after debridement and bandage, and then covered it with sterile gauze; the control group used 0.5% amriodine conventional dressing change method, and covered it with sterile gauze after debridement and bandage. Wound healing time, effective rate and gauze adhesion rate of two groups of trauma patients. Results The traumatic wound healing time in the treatment group was shorter than that in the control group [(3.57±1.43)d vs. (4.80±1.61)d, P<0.05], and the effective rate was higher than that in the control group (98.6% vs.79.7%, P<0.05 ), while the gauze adhesion rate was lower than that of the control group (66.2% vs. 93.2%, P < 0.05), and the number of dressing changes was less than that of the control group (2.49 ± 0.76 vs. 1.81 ± 0.75, P < 0.05). Conclusion Fonow ointment (Compound Polymyxin B Ointment, Triple Antibiotic Ointment) has a significant healing effect in treating traumatic wounds. It can shorten the healing time, reduce wound tension, and will not stretch the wound when removing the gauze, which reduces the patient's pain. It is easy and safe to use.
Zhao Shuang, Wang Meiling, Zhang Xiaotong. Application of compound polymyxin B ointment in wound dressing change[J]. Practical Drugs and Clinics, 2016, 19(04): 467-470.